Quaternary ammonium salt

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Tetrabutylammonium bromide

Tetrabutylammonium bromide
CAS No.: 1643-19-2
Molecular Formula: C16H36BrN
Molecular Weight: 322.37
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Product Introduction

Tetrabutylammonium bromide is an environmentally benign, non-volatile, non-flammable, non-corrosive, low-cost, commercially available ammonium salt with high thermal and chemical stability. In TBAB, tetrabutylammonium salt can dissolve in both aqueous as well as in organic solvents, which helps to transport the water-soluble anionic reactants into the organic phase. Moreover, molten TBAB was also employed as an efficient ionic liquid to carry out organic transformations under solvent-free conditions.


CHEMICAL PROPERTIES

PropertyValue

Melting Point

102-106 °C(lit.)

Boiling Point

102 °C

Density

1.039 g/mL at 25 °C

Bulk Density

700kg/m3

Vapor Pressure

0Pa at 25℃

Refractive Index

n20/D 1.422

Fp

100℃

Storage Temp.

Store below +30°C.

Solubility

H2O: 0.1 g/mL, clear, colorless

Form

Crystalline Powder

Pka

0[at 20 ℃]

Specific Gravity

1.007

Color

White to slightly cream

Odor

Amine like

PH

3.5 to 7.0 (50 g/L, 25 ℃)

Water Solubility

600 g/L (20 ºC)

Sensitive

Hygroscopic

λmax

λ: 240 nm Amax: 0.04λ: 250 nm Amax: 0.03λ: 260 nm Amax: 0.02λ: 500 nm Amax: 0.02

BRN

3570983

Stability:

Stable. Incompatible with strong oxidizing agents. Protect from moisture.

InChIKey

JRMUNVKIHCOMHV-UHFFFAOYSA-M

LogP

0.839 at 25℃

CAS DataBase Reference

1643-19-2(CAS DataBase Reference)

NIST Chemistry Reference

Tetra-N-butylammonium bromide(1643-19-2)

EPA Substance Registry System

Tetrabutylammonium bromide (1643-19-2)


SAFETY INFORMATION

PropertyValue
Hazard symbolsXi, Xn
Hazard class codes36/37/38-22
Safety descriptions26-36-37/39
WGK Germany3
F3
Hazard NoteIrritant
TSCATSCA listed
HS code29239000
Storage class11 - Combustible solids
Hazard class (categories)Acute toxicity, Category 4, Oral
Hazardous to the aquatic environment — long-term hazard, Category 3
Eye irritation, Category 2
Reproductive toxicity, Category 2
Skin irritation, Category 2


PRODUCT USAGE

Tetrabutylammonium Bromide (TBAB for short), with CAS No. 1643-19-2 and chemical formula C₁₆H₃₆BrN, appears as white crystalline powder, easily soluble in solvents such as water, ethanol and acetone, and is a commonly used quaternary ammonium salt phase transfer catalyst. Its core application is in the field of organic synthesis. As an efficient phase transfer catalyst, it can effectively promote the reaction between aqueous and organic phases, accelerate the progress of nucleophilic substitution, redox, elimination and other reactions, greatly improve reaction rate and yield, and is widely used in fine chemical fields such as drug synthesis, spice preparation and dye synthesis. In the electrochemical field, it can be used as a supporting electrolyte for non-aqueous electrolytes to improve electrolyte conductivity. In addition, it is used as an ion-pair reagent in the field of chemical analysis to assist chromatographic separation, and is also used as an intermediate in organic synthesis and surfactant, serving as an indispensable special chemical raw material in fine chemical and electrochemical fields.

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