1,3-Propanediol, also known as 1,3-dihydroxypropane, is an organic compound with the chemical formula C₃H₈O₂ and CAS number 504-63-2. At room temperature, it appears as a colorless, transparent, viscous liquid with a melting point of -27°C, a boiling point of 210~211°C, and a density of 1.05 g/cm³. It is miscible with water, ethanol, and ether. This substance is primarily used in the synthesis of polytrimethylene terephthalate (PTT), pharmaceutical intermediates, and antioxidants, and serves as a humectant and solvent in cosmetics.

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As a diol, 1,3-propanediol is subject to many of the same polymeric applications as other low molecular mass diols (e.g., ethylene glycol, propylene glycol, and 1,4-butanediol). However, its relatively high price limits its use to applications requiring very specific performance characteristics. It is a raw-material source for 1,3-dioxanes. 1,3-Propanediol-bis(4-aminobenzoate) can be used as a chain extender in polyurethane elastomers. This bisbenzoate, which can also be synthesized from 1,3-dichloro-propane, finds other applications as a cross-linking agent in epoxy formulations and as a rubber additive.