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Arbutin

Arbutin
CAS No.: 497-76-7
Molecular Formula: C12H16O7
Molecular Weight: 272.25
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+86 18765828098
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Product Introduction

Arbutin is a β-D-glucopyranoside HQ derivative and a plant-derived compound found in the dried leaves of several plant species, including blueberry, cranberry, bearberry, and pear trees. It suppresses tyrosinase activity without altering RNA expression.


CHEMICAL PROPERTIES

PropertyValue

Melting point

195-198 °C

Alpha

-64 º (c=3)

Boiling point

375.31°C (rough estimate)

Density

1.3582 (rough estimate)

Refractive index

-65.5 ° (C=4, H2O)

Storage temp.

Inert atmosphere,Room Temperature

Solubility

H2O: 50 mg/mL hot, clear

Pka

10.10±0.15(Predicted)

Form

Solid

Color

White

Biological source

Synthetic or plant

Optical Rotation

[α]/D -64.0±2.0°, c = 3 in H2O

Water Solubility

10-15 g/100 mL at 20 ºC

Sensitive

Hygroscopic

Merck

14,773

BRN

89673

Stability

Stable. Hygroscopic - store under dry nitrogen.

InChIKey

BJRNKVDFDLYUGJ-RMPHRYRLSA-N

LogP

-1.350

CAS DataBase Reference

497-76-7(CAS DataBase Reference)

EPA Substance Registry System

.beta.-D-Glucopyranoside, 4-hydroxyphenyl (497-76-7)


SAFETY INFORMATION

PropertyValue
Hazard CodesXn
Risk Statements20/21/22-36/37/38
Safety Statements22-24/25-36-26
WGK Germany3
RTECSCE8863000
F2003/10/23
HS Code29389090
Hazardous Substances Data497-76-7(Hazardous Substances Data)


PRODUCT USAGE

Arbutin, a naturally derived hydroquinone glucoside typically extracted from bearberry leaves, is a premier active ingredient in the global cosmetic and skincare industry. It is primarily utilized as a safe and effective skin-lightening agent in brightening serums, whitening creams, and spot-correction treatments. By competitively inhibiting tyrosinase activity, it effectively suppresses melanin production to fade hyperpigmentation, melasma, and post-inflammatory dark spots. In the personal care sector, Arbutin is highly valued for its dual functionality, offering both depigmenting effects and potent antioxidant properties that protect the skin against oxidative stress induced by UV radiation. Furthermore, its mild nature compared to synthetic alternatives makes it an ideal component for sensitive skin formulations and high-end dermo-cosmetics aimed at evening out skin tone and restoring a youthful, radiant complexion.

Factory Showcase
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FAQ

Q: Are you a factory or a trading company?

A: We are a company integrating manufacturing and trading.

Q: Can you provide samples for testing before mass production?

A: Of course. We can send you samples free of charge, and we also include a COA. However, you will be responsible for the shipping fee.

Q: How can I get an accurate quote?

A: Please provide the exact product specifications, particle size, color, and intended use, and we will provide you with an accurate quote.

Q: Can you provide a COA?

A: Of course, but only for standard products. If you require an accurate COA, we will produce and test samples before providing you with an accurate COA.

Q: Do you accept ODM or OEM services?

A: Yes, we offer customized services for ingredients, packaging, and labeling. We have strong design capabilities. Please contact us to design your own brand.

Q: Can I visit your factory before placing a large order?

A: Of course. We welcome you at any time.

Q: What is the loading port?

A: Usually Qingdao or Tianjin.

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