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L-Tryptophan

L-Tryptophan
CAS No.: 73-22-3
Molecular Formula: C11H12N2O2
Molecular Weight: 204.23
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Product Introduction
L-tryptophan is the L-enantiomer of tryptophan. It has a role as an antidepressant, a nutraceutical, a micronutrient, a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is an erythrose 4-phosphate/phosphoenolpyruvate family amino acid, a proteinogenic amino acid, a tryptophan and a L-alpha-amino acid. It is a conjugate base of a L-tryptophanium.


CHEMICAL PROPERTIES

PropertyValue

Melting point

289-290 °C (dec.)(lit.)

Alpha

-31.1 º (c=1, H20)

Boiling point

342.72°C (rough estimate)

Density

1.34

Bulk density

400kg/m3

Refractive index

-32 ° (C=1, H2O)

Storage temp.

2-8°C

Solubility

20% NH3: 0.1 g/mL at 20 °C, clear, colorless

Form

Powder

Pka

2.46(at 25℃)

Color

White to yellow-white

PH

5.5-7.0 (10g/l, H2O, 20℃)

Odor

wh. cryst. or cryst. odorless powd., sl. bitter taste

Biological source

Non-animal source

Optical Rotation

[α]20/D 31.5±1°, c = 1% in H2O

Water Solubility

11.4 g/L (25 ºC)

Merck

14,9797

BRN

86197

Stability

Stable. Incompatible with strong acids, strong oxidizing agents.

InChIKey

QIVBCDIJIAJPQS-VIFPVBQESA-N

LogP

0.704 (est)

CAS DataBase Reference

73-22-3(CAS DataBase Reference)

NIST Chemistry Reference

L-Tryptophan(73-22-3)

EPA Substance Registry System

L-Tryptophan (73-22-3)

Absorption

cut-off at 326nm in 0.5 M HCl at 0.5M


SAFETY INFORMATION

PropertyValue

Hazard Codes

Xi

Risk Statements

33-40-62-41-37/38-36/37/38-22

Safety Statements

24/25-36/37/39-36-26

WGK Germany

2

RTECS

YN6130000

F

8

TSCA

Yes

HS Code

29339990

Hazardous Substances Data

73-22-3(Hazardous Substances Data)

Toxicity

LD508mmol / kg (rat, intraperitoneal injection). It is safe when used in food (FDA, §172.320, 2000).


PRODUCT USAGE

L-Tryptophan is an essential amino acid and a vital precursor to serotonin and melatonin, making it indispensable in the nutraceutical and pharmaceutical industries. Its primary application is in dietary supplements designed to improve sleep quality, regulate mood, and alleviate anxiety. In infant nutrition, it is a mandatory additive in formulas to ensure healthy neurological development and sleep-wake cycles. The animal feed industry also utilizes L-Tryptophan extensively as a growth promoter and stress-reducer for livestock and aquaculture, enhancing feed efficiency. Furthermore, it serves as a high-value chemical intermediate in the synthesis of specialized drugs and biochemical reagents. In cosmetics, it is occasionally used in anti-aging formulations for its potential antioxidant properties and role in skin repair.

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Q: What is the loading port?

A: Usually Qingdao or Tianjin.

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