Tocopherol succinate (4345-03-3) is a potent antioxidant.  Protects mice from gamma-radiation by induction of granulocyte-colony stimulating factor.1,2? Tocopherol succinate induces apoptosis in human gastric cancer cells3? and inhibits proliferation of mesothelioma cells by down-regulation of fibroblast growth factor receptor-14.  Induces apoptosis in neuroblastoma cells.5

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PRODUCT USAGE

D-α-Tocopherol succinate, a solid derivative of natural Vitamin E, is highly valued for its superior stability and potent biological activity. Its primary application is in the pharmaceutical and nutraceutical industries, where it is a preferred form of Vitamin E for high-end dietary supplements, tablets, and hard capsules due to its non-oily, crystalline nature. Beyond basic nutritional fortification, it is extensively researched and utilized for its anti-tumor properties and ability to induce apoptosis in cancer cells without harming normal tissues. In the cosmetic sector, it serves as a powerful antioxidant and skin-conditioning agent, protecting cell membranes from oxidative damage and UV-induced stress. Furthermore, it is used in functional foods and animal nutrition to enhance shelf life and support immune function, offering better resistance to heat and oxidation compared to liquid Vitamin E.