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Acrylamide

Acrylamide
CAS No.: 79-06-1
Molecular Formula: C3H5NO
Molecular Weight: 71.08
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+86 18765828098
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Product Introduction

Acrylamide is an important organic synthetic monomer, which combines chemical reactivity with specific physical properties. At room temperature, it is a white crystalline powder. Pure products are odorless, while industrial products may have a slightly pale yellow or pungent smell due to the presence of trace impurities. Crystals are prone to absorbing moisture and gradually soften or even dissolve after absorbing it.


CHEMICAL PROPERTIES

PropertyValue
Melting point82-86 °C(lit.)
Boiling point125 °C25 mm Hg(lit.)
Density1,322 g/cm3
Bulk density500kg/m3
Vapor density2.45 (vs air)
Vapor pressure0.03 mm Hg ( 40 °C)
Refractive index1.46
Fp138 °C
Storage temp.2-8°C
Solubility2040 g/L (25°C)
Formpowder
Pka15.35±0.50(Predicted)
ColorWhite
OdorOdorless solid
PH5.0-7.0 (50g/l, H2O, 20℃)
Water SolubilityAcrylamide is routinely tested at 250 mg/mL in water, giving a clear colorless solution. It is soluble at least to 40% (w/v) in water, and reportedly up to 215 g/100 mL in water at 30°C.
SensitiveLight Sensitive
Merck14,129
BRN605349
Henry's Law Constant(x 10-9 atm?m3/mol): 3.03 at 20 °C (approximate - calculated from water solubility and vapor pressure)
Exposure limitsPotential occupational carcinogen. NIOSH REL: TWA 0.03, IDLH: 60; OSHA PEL: TWA 0.3; ACGIH TLV: TWA 0.03.
StabilityUnstable. Do not heat above 50C. Explosive. Incompatible with acids, bases, oxidizing agents, reducing agents, iron and iron salts, copper, aluminium, brass, free radical initiators. Air sensitive. Hygroscopic.
InChIKeyHRPVXLWXLXDGHG-UHFFFAOYSA-N
LogP-0.9 at 20℃ and pH7
CAS DataBase Reference79-06-1(CAS DataBase Reference)
NIST Chemistry ReferenceAcrylamide(79-06-1)
IARC2A (Vol. 60, Sup 7) 1994
EPA Substance Registry SystemAcrylamide (79-06-1)


SAFETY INFORMATION

PropertyValue
Hazard symbolT
Hazard class codes45-46-20/21-25-36/38-43-48/23/24/25-62-48/20/21/22-22-24/25
Safety descriptions53-45-24-36/37/39-26-36/37
UN dangerous goods number (solid)UN 2074 6.1/PG III (ACRYLAMIDE, SOLID)
UN dangerous goods number (solution)UN 3426 6.1/PG III (ACRYLAMIDE SOLUTION)
Occupational exposure classD
Occupational exposure limitTWA: 0.03 mg/m³ [skin]
WGK Germany3
RTECS numberAS3325000
F8-10
Autoignition temperature424°C
TSCATSCA listed
Hazard class6.1
Packing groupIII
HS code29241900
Storage class6.1C - Combustible, acute toxicity Category 3
Toxic compounds or compounds causing chronic effects
Hazard class (category)Acute toxicity, Category 3, Oral
Acute toxicity, Category 4, Dermal
Acute toxicity, Category 4, Inhalation
Carcinogenicity, Category 1B
Eye irritation, Category 2
Germ cell mutagenicity, Category 1B
Reproductive toxicity, Category 2
Skin irritation, Category 2
Skin sensitization, Category 1
Specific target organ toxicity — repeated exposure, Category 1, Oral
Hazardous substances data79-06-1 (Hazardous Substances Data)
ToxicityLD50 i.p. in mice: 170 mg/kg (Peterson, Sheth)
Immediately dangerous to life or health concentration

60 mg/m³


PRODUCT USAGE

Acrylamide is a vital organic monomer primarily used in the synthesis of polyacrylamide (PAM), a versatile polymer with extensive industrial utility. Its most significant application is in water treatment, where PAM acts as a high-efficiency flocculant for municipal sewage and industrial wastewater purification. In the petroleum industry, it is a key component for enhanced oil recovery (EOR) and as a friction reducer in hydraulic fracturing. In paper manufacturing, acrylamide-based resins serve as retention aids and dry-strength agents to improve paper quality. Furthermore, in biotechnology and clinical labs, high-purity acrylamide is indispensable for preparing polyacrylamide gels used in electrophoresis (PAGE) for the separation of proteins and nucleic acids.

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