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Potassium phosphate

Potassium phosphate
CAS No.: 7778-53-2
Molecular Formula: K3PO4
Molecular Weight: 212.266261
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Product Introduction

Potassium phosphate is a reagent with high buffering capacity, It serves as a buffering agent to regulate pH, Typically used as a component for a wide variety of media used in the culture of microorganisms, as a component in phosphate buffered saline (PBS). It occurs in several forms: monobasic, dibasic, and tribasic (K3PO4). Most pH neutral potassium phosphate buffer solutions consist of mixtures of the monobasic and dibasic forms to varying degrees, depending on the desired pH. Gomori buffers, the most commonly used phosphate buffers, consist of a mixture of monobasic dihydrogen phosphate and dibasic monohydrogen phosphate. By varying the amount of each salt, a range of buffers can be prepared that buffer well between pH 5.8 and pH 8.0 (please see the tables below). Phosphates have a very high buffering capacity and are highly soluble in water.

Potassium phosphate is used as a fertilizer and food additive. It is also used in optical modulators and for non-linear optics such as second-harmonic generation (SHG). It is involved in the phase-transfer catalyzed preparation of acetylenes from the corresponding vicinal dibromo compounds through double dehydrobromination. It is also useful for the oxidative coupling of thiols to disulfide.

Potassium phosphate tribasic is a reagent with a very high buffering capacity. It is widely used in molecular biology, biochemistry, and chromatography, used for the extraction of keratohyalin protein from bovine tissue, to study the effects of freezing and thawing on the stability of proteins sensitive to conformational changes. It is used as a food additive for its properties as an emulsifier, foaming agent, and whipping agent.

Potassium phosphate tribasic has been used:

in lysis buffer for the isolation of protein from Gram positive bacteria

as a reagent for the scalable synthesis and post-modification of NU-1000 (mesoporous metal-organic framework)

as a reagent for the plasma membrane preparation of Lilium davidii or Oryza sativa with high purity


CHEMICAL PROPERTIES

PropertyValue

Melting point

1340 °C

Density

2.564 g/mL at 25 °C(lit.)

Vapor pressure

0Pa at 20℃

Storage temp.

Room temp

Solubility

water: soluble100mg/mL, clear, colorless

Form

Solid

Specific Gravity

2.564

Color

White

Odor

At 100.00%. odorless

Water Solubility

50.8 g/100 mL (25 ºC)

Sensitive

Hygroscopic

Merck

14,7660

BCS Class

1

Stability:

Stable. Incompatible with strong oxidizing agents, moisture.

CAS DataBase Reference

7778-53-2(CAS DataBase Reference)

EPA Substance Registry System

Tripotassium phosphate (7778-53-2)


SAFETY INFORMATION

PropertyValue
Hazard CodesC,Xi
Risk Statements38-41-34
Safety Statements26-39-45-36/37/39
RIDADRUN 1805 8/PG 3
WGK Germany2
RTECSTC8450000
F8-10
TSCAYes
HS Code28352400


PRODUCT USAGE

Potassium Phosphate refers to a group of salts composed of phosphorus and potassium (such as MKP and DKP), serving multiple critical roles in modern production. In the food industry, it acts as a superior acidity regulator, emulsifier, and moisture-retention agent, widely used in instant beverages, dairy products, and meat processing to optimize texture and extend shelf life. In agriculture, it is a premium, 100% water-soluble phosphorus-potassium compound fertilizer that significantly enhances crop disease resistance and promotes flower bud differentiation. Within medicine and biotechnology, it is frequently employed as a pH buffering agent to regulate pharmaceutical environments or as a nutrient source in microbial culture media. Additionally, it is used industrially as a metal surface treatment agent and a raw material for specialized coatings.

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